Avian Influenza Low Pathogenic (LP ...

Avian Influenza Low Pathogenic (LPAI) Moderately Virulent of any H 1-16 or N 1-9 subtype in Laying Hens

The moderately virulent clinical group results from infection by Low Pathogenic avian influenza (LPAI) virus of any HA or NA subtype, but also with co-infection by secondary pathogens. The mortality rates are usually less than 5% unless accompanied by secondary pathogens as well as in reproductively active hens, or severely stressed birds. Clinical signs reflect abnormalities in the respiratory, digestive, urinary and reproductive organs. The most frequent signs represent infection of the respiratory tract and include mild to severe respiratory signs such as coughing, sneezing, rales, rattles, and excessive lacrimation. Egg production is decreased and increased broodiness. The generalized clinical signs including huddling, ruffled feathers, depression, decreased activity, lethargy, decreased feed and water consumption, and occasionally diarrhea.  The last few eggs laid will have reduction in calcium deposition within the eggshells. Resulting eggs may be misshapen and fragile with loss in pigmentation.

High morbidity (percentage of sick birds) and low mortality are typical. Mortality rates are usually less than 5% unless accompanied by secondary pathogens such as Pasteurella multocida or Escherichia coli.

Causing Agents
Viral infection. Avian Influenza (AI) virus, family Orthomyxoviridae, genus Influenzavirus A. LPAI ("low pathogenic avian Influenza")
Affected Systems/Organs
Respiratory, digestive, urinary and reproductive organs
Bird to bird, contaminated water and objects from infected birds. The virus is transmitted by direct contact between infected and susceptible birds or indirect contact through aerosol droplets or exposure to virus-contanminated fomites. The virus is excreted from the nares, mouth, conjunctiva, and cloaca of infected bird into the environment because the virus replication in the respiratory, intestinal, renal, and/or reproductive organs.
Mainly Affects
Liveability and egg production
Biosecurity and hygiene programs and an 'All-in/All-out' approach to production. Vaccination with Inactivated H5 and H7 vaccine and a fowl pox-AI hemagglutinin (H5) recombinant vaccine (rFP-AI-H5).
Suggested Actions
  • Can be confirmed with clinical signs and gross lesions
  • Can be managed with vaccination programs
  • Diagnosis should be confirmed with rapid assays and/or a certified laboratory
  • Veterinary intervention is recommended
  • This is a notifiable disease, veterinary intervention is essential. It is advisable that you run DTECT again to ensure you have answered all the questions correctly. If you suspect that you may have this disease please contact your local authorities immediately.

Impact on Egg quality


Impact on Liveability


Impact on Production


Overall Economic Impact


Y.M. Saif.2008.Disease of Poultry. 12th Edition.

Mark Pattison, Paul F. McMullin, Janet M. Bradbury. Dennis J. Alexander. 2008. Poultry Diseases. 6th Edition.

Paul McMullin. 2004. A pocket Guide to Poultry Health and Disease. First Edition.

Steven Leeson, John D. Summers. 2008. Commercial Poultry Nutrition. Third Edition.

Donald D. Bell, Williams D. Weaver. 2009.  Commercial Chicken Meat and Egg Production. Fifth Edition.

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